A Multi-Center Randomized Trial of Transanastomotic Tube for Proximal Esophageal Atresia and Distal Tracheoesophageal Fistula Repair

October 21, 2021

The use of trans-anastomotic nasogastric tubes following esophageal reconstruction in esophageal atresia is controversial.  Advocates of trans-anastomotic tubes argue that the tubes allow for earlier enteral feedings and function as a stent to maintain patency of the anastomosis.  However, retrospective studies suggest that trans-anastomotic tubes increase the risk of anastomotic strictures.  This prospective trial randomizes patients into tube vs no-tube treatment groups, with the primary endpoint of anastomotic stricture formation at 1-year post-operatively.